Perbandingan Akurasi Diagnostik PHQ-2 dan PHQ-9 sebagai Instrumen Skrining Depresi di Layanan Primer: Systematic Literature Review

Moch. Tabriz Azenta; Burhanudin Ichsan; Shalsa Difa Permatasari; Nabila Mutia Salsabila; Nabila Humaira; Chevalerie Daffa Prawito; Natasya Pramono

doi:10.56211/pubhealth.v4i3.1415

Authors

Moch. Tabriz Azenta Universitas Muhammadiyah Surakarta, Surakarta
Burhanudin Ichsan Universitas Muhammadiyah Surakarta, Surakarta
Shalsa Difa Permatasari Universitas Muhammadiyah Surakarta, Surakarta
Nabila Mutia Salsabila Universitas Muhammadiyah Surakarta, Surakarta
Nabila Humaira Universitas Muhammadiyah Surakarta, Surakarta
Chevalerie Daffa Prawito Universitas Muhammadiyah Surakarta, Surakarta
Natasya Pramono Universitas Muhammadiyah Surakarta, Surakarta

DOI:

https://doi.org/10.56211/pubhealth.v4i3.1415

Keywords:

Depresi; Layanan primer; PHQ-2; PHQ-9; Skrining

Abstract

Deteksi dini depresi di layanan primer membutuhkan instrumen skrining yang akurat sekaligus praktis. Tinjauan sistematis ini membandingkan akurasi diagnostik Patient Health Questionnaire-2 (PHQ-2) dan PHQ-9 untuk skrining depresi. Pencarian dilakukan di Google Scholar dan PubMed dengan kata kunci terkait (publikasi 2020-2025). Seleksi menggunakan alur PRISMA dengan kriteria inklusi studi komparatif pada dewasa di layanan primer. Lima studi (6.500 subjek) dari berbagai populasi memenuhi kriteria. PHQ-9 menunjukkan sensitivitas lebih tinggi (0,88-0,90) dibandingkan PHQ-2 (0,75-0,80), dengan spesifisitas masing-masing 0,85 dan 0,78. PHQ-2 efektif untuk skrining awal dengan administrasi lebih cepat, sedangkan PHQ-9 memberikan evaluasi komprehensif untuk diagnosis definitif. Pendekatan bertingkat mengoptimalkan deteksi dini dengan menggunakan PHQ-2 sebagai skrining awal dilanjutkan PHQ-9 untuk evaluasi mendalam. Disarankan menggunakan pendekatan dua tahap (two-step screening): PHQ-2 untuk skrining cepat semua pasien, lalu lanjutkan PHQ-9 pada hasil positif untuk konfirmasi.

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